ActiFolate is Metagenics proprietary blend o L-5 methyl tetrahydrofolate (L-5-MTHF), 5-formyl erahydrofolate (5-formyl THF), and folic acid.  This all inclusive, bioavailable source of folate nutrition is perfect or patients who require general folate supplementation. Encourages methylation pathways at various points of folate metabolism, which may beter support overall methylation than a single form of folate-especially in those with genetic variations in folate metabolism. Features L-5-MTHF, a body-ready, nature identical folate that crosses the blood-brain barrier. Encourages overall good health by promoting cardiovascular health, mental function, detoification, maintenance of DNA, prenatal health and breast health. Delivers the vbiologically active folates that are most commonly found in vegetables. Critical for people whose folate status may be affected by genetic variation