Yes, It is believe to be caused by estrogen dominance. Estrogen stimulate their growth. Some signs of estrogen dominance in ratio to progesterone deficiency common with peri-menopause are breast swelling, fibrocystic breasts, water retention, weight gain, (around the hips) depression, low sex drive. According to Dr. Lee, Natural progesterone can help keep them from growing.

There is a link between hormone imbalance and uterine fibroids.
Hormone imbalance or estrogen dominance causes the uterus to grow unchecked that may be the cause fibroids tough fibrous, noncancerous lumps that may cause heavy, constant bleeding.  During peri-menopause, Fibroids can grow, which is stimulated by too much estrogen in the body. Large fibroids create estradiol (the most potent form of estrogen) inside the lump, leading to more estrogen dominance.

Maintaining a balance of estrogen to progesterone is especially important during peril-menopause years. Some of the average size fibroids can be am undetectable lump in the wall of the uterus, about the size of a hens egg. However, larger fibroids often cause irregular bleeding and heavy, or painful periods.

If you have excessive bleeding during menstruation, fibroids are commonly the reason. If you have this condition of estrogen dominance it would the use of bio-identical progesterone may counter estrogen buildup. If you feel you have larger fibroids, discuss it with your physician.

Natural progesterone cream works on the whole hormonal system.